Not if you don't bring him in from after canon is complete.

I'm walking a fine line with him. I brought him in after he killed Vicious but before he made it all the way down the steps.

Wiggle room. Even Watanabe-san said something like "Spike sleeps a lot, so maybe he's just sleeping." Of course, I think he was just being evasive. I think over is over, but I'm not playing him from that point in canon. Just like when I played Vicious, it was from before his bird sacrificed himself to cause a distraction. So... it's all a question of which point in canon you're playing from.

With Spike, there are so many theories. So many. That's a whole other discussion, though.